How often should I take CLEANSE ? How often should I take CLEANSE ? Can I use too much CLEANSE ? Is the CORE Boost CLEANSE safe to use? Posted by Joe Jerde on June 16, 2014 in Use CLEANSE once a day for seven days. If you re-start the program, you could use it again. It is not recommended to use for prolonged periods of time. Tags:core boost cleanse Share this article: About Joe Jerde I'm an entrepreneur looking forward to meeting new people and helping them become successful in building their own business!